Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or research is crucial for making sure the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound inside the synthesis of imatinib, a drug that targets particular types of cancer, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is vital for optimizing the production approach and ensuring significant purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to take care of breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Utilized in the treatment of breast cancer. A variety of intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a CAS NO. 114611-53-9 chemotherapy drug powerful in dealing with cancers which include ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal cancer and small mobile lung cancer.
three-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, that have numerous programs, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-4 to 5-dibenzoate(T6) manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is linked to the synthesis of assorted gluconic acid derivatives, that are used in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor from the synthesis of canagliflozin, a medication applied to control variety 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).